While others are concerned on the possible side effects of steroids to the body, there is a new research that also make this substance a promising aid in preventing diseases especially heart related problems. In the previous months, there were studies saying that the long term use of steroids can lead to kidney problems and become harmful to the heart when used for longer periods. This may be true since abuse of any drug can really be detrimental to one’s health.

However, this new finding could give some hope to people who are suffering from heart diseases or could be a better alternative in preventing heart diseases. According to researchers at the University of Leeds, UK, a natural defense mechanism against heart disease could be triggered by steroids sold as health supplements.

Biologists from the University have identified a previously-unknown ion channel in human blood vessels that can limit the production of inflammatory cytokines. These cytokines are proteins that contribute to the early onset of heart disease. But the study was only referring to a particular type of steroid. Steroids which are called “fountain of youth” are said to improve one’s energy, memory and vision.

DHEA and pregnenolone sulphate were identified to help people prevent heart disease. Some pharmaceutical companies market these steroids as “fountain of youth” supplements because of the benefit it gives to the user. These steroids were also banned in most sporting organization especially in sports which requires physical ability and concentration.

Experts said that these steroids are made naturally in the body. However, as one gets older, its production in the body declines. Thus health supplements containing these compounds become popular.

In a collaborative study by Leeds General infirmary surgeons, the finding also shows that the defense mechanism can be switched on in diseased blood vessels as well as in healthy vessels. According to Professor David Beech who led the study, the effect that they have seen is really quite exciting and unexpected. “However, we are absolutely not endorsing any claims made by manufacturers of any health supplements. Evidence from human trials is needed first,” Beech said.

Researchers also discovered that these steroids were not effective if cholesterol was also present based on their chemical profiling. They suggest that administration of cholesterol-lowering drugs together with DHEA or pregnenolone will improve the protective effects of these steroids. Healthy lifestyle such as proper diet and regular exercise were also recommended.

Professor Beech noted that these steroids are relatively cheap to make and some of these are already commercially available. “So if we can show that this effect works in people as well as in lab-based studies, then it could be a cost-effective approach to addressing cardiovascular health problems that are becoming epidemic in our society and world-wide,” Beech added.

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