Arimidex (anastrozole) is an approved medication prescribed to postmenopausal women who have hormone receptor-positive breast cancer in the early stages. As an aromatase inhibitor, Arimidex (anastrozole) works by blocking the aromatase enzyme to prevent estrogen from being produced.
Menopause, cancer, and arimadex
In a series of reactions, the body's adrenal gland makes a number of hormones, including estrogens and androgens. When women go through menopause, their ovaries stop producing estrogen. Most of the needed estrogen then in the body is made by changing androgens to estrogens. With the help of the aromatase enzyme, androgen is converted to estrogen in different places in the body, like the muscles, fats, and liver, and even in breast tumors. Since estrogen promotes the growth of certain breast tumors, Arimidex (anastrozole) comes into play by binding to aromatase, stopping or inhibiting the enzyme's activity, and therefore estrogen production. Stop the estrogen supply and you help stop the cancer.
After clinical trials, results show that the most common side effects of using Arimidex (anastrozole) include joint symptoms, hot flashes, weakness, body pains, mood swings, sore throats, vomiting and nausea, high blood pressure, depression, osteoporosis, headaches, and swelling of the arms and legs. Since bones are weaker, fractures, including those in the wrist, hip, and spine, also occurred more frequently. While side effects are inevitable, as with any kind of medication, the ones you experience with Arimidex remain to be quite manageable. For example, swelling. To cope with swelling, avoid using the affected arm to carry or lift shopping bags or other heavy objects and always use gloves when you're washing dishes or gardening to protect against infections. Avoid wearing tight accessories and clothes on your affected arm and wear compression sleeves to help in pooling the fluid to be drained. To maintain your range of motion and flexibility, do regular, gentle exercises.
Arimidex for men
Arimidex (anastrozole) may also be utilized as an ancillary compound that is to be added to a steroid cycle. For this purpose, it is advantageous to use because as it reduces estrogen in the body, it also increases testosterone levels. Since aromatization (estrogen conversion) is avoided, those who use Arimidex also avoid estrogen-related side effects such as water retention, acne, and gynecomastia (male breast enlargement). Nonetheless, enough estrogen is still left in the body, just enough to attain optimal muscle growth.
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