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time   Friday, November 22, 2019 05:25
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Dianabol - A Trusted Ally in Body Building:

The second anabolic steroid ever made, Methandrostenolone, more popularly known to bodybuilders as Dianabol or Dbol, has been around since 1958 when it was introduced by John Ziegler and Ciba. It is one of the most popular AAS (anabolic androgenic steroid) used by bodybuilders, and remain so today- a decade after its production in the US had been discontinued.

It’s quite easy to see why. Dbol is both anabolic (muscle-building) and androgenic (masculinizing), but it is the former attribute that draws loyal patronage, particularly from bodybuilding enthusiasts. It is an altered version of testosterone: c17 alpha alkylated, to allow it to pass through the liver without being deactivated dinabol pillsand be able to enter the blood stream while the added 1-2 double carbon bond slows aromatization (conversion to estrogen). This substance reacts poorly with the androgen receptor [1], and thus depends on non-receptor mediated activities, such as marked and immediate increases in protein synthesis (resulting in nitrogen-filled muscle buildup), restoration of glycogen after training (glycogenolysis), and muscle strength. It is for these reasons that users favor Dbol specifically to jumpstart steroidal cycles – as its offers immediate tangible results - while the effects of other substances stacked with it are observed weeks into the cycle.
 
There are known side effects to Dianabol: potential liver damage brought about by the alpha alkylated carbon; gynecomastia (development of breast tissues); increased water retention; high blood pressure; male pattern baldness for susceptible people; and for women, masculinizing effects such as deep voice, oily skin, acne and growth of body and facial hair. For these reasons, extraordinary care should be taken when taking Dbol and long-term use is not at all advised. Still, this is a relatively safe drug when taken in cycles and in correct doses, though there had been studies where subjects took pretty high doses of Dianabol and they didn’t suffer any intolerable side effects [2]. 

Cycles and stacking programs have been developed to precisely address these concerns and minimize the harmful effects – these usually involve use of Dianabol in the initial stages of a steroid cycle, then later on relying on less liver-damaging substances to improve or sustain the gains from Dbol. This is common in bulking programs used by bodybuilding buffs: Dianabol (oral) is used together with longer-lasting injectables (such as Testosterone Cypionate or Deca-Durabolin) typically in the first four weeks of the cycle. Dbol quickly beefs-up muscle mass while the other drugs take longer to have observable effects. After four weeks, the body has built enough muscle gains and the effects of the other drugs are now being felt, so Dbol is discontinued for the rest of the cycle while other drugs may be introduced, such as Equipoise which is considered a good lean-mass building steroid if well-defined muscles is the goal.

Undoubtedly, loyal users have weighed the advantages of using Dianabol versus the potential risks, and its continued popularity clearly indicates that the gains one gets in using this substance is worth the risk. To minimize hazards, users take ancillary drugs to control the harmful androgenic effects; anti-estrogen drugs (Nolvadex, Clomid) or aromatase inhibitors (Arimidex, Aromasin) are taken to keep the estrogen under control and avoid gynecomastia and other androgenic conditions brought forth by Dianabol and other stacked testosterones. To avoid liver damage, moderate doses should be taken up to six weeks (recommended duration) and regular medical visits should be done to check of jaundice and other signs of liver dysfunctions. 

Dianabol is currently being manufactured in Mexico (marketed as Reforvit-b), Russia and Thailand and is available on online stores. Note that there is a supplement currently marketed with the same name (the company, Hi-Tech Pharmaceuticals, bought the trademark after the original owner, Ciba-Geigy allowed it to expire [3]). One must be careful to order the Dianabol (methandrostenolone) if one needs a straightforward steroid, and not the supplement which has some steroidal effects. 

 

  1. The effect of anabolic-androgenic steroids on aromatase activity and androgen receptor binding in the rat preoptic area. Brain Research 1998 May 11;792(2):271-6.
  2. Clin Sci (Lond). 1981 Apr;60(4):457-61.
  3. New York Daily News. Beating the Heat by Michael O'Keeffe & T.J. Quinn. December 25, 2005.